杂原子化学的设计目的是将一个广泛的跨学科的化学家群体聚集在一起，他们与含有周期表第13至17组的主要基团元素和某些其他相关元素的化合物一起工作。基本反应性在所有情况下都应该集中在杂原子上。无论所研究的化合物是无环的还是环状的；饱和的还是不饱和的；具有单体聚合物或固态性质的；无机有机的或自然存在的，只要杂原子起着至关重要的作用。同时欢迎实验文章和基于计算化学的文章。一般来说，杂原子化学不接受基于经典杂环化学的手稿（有几种特殊期刊可供查阅）。它欢迎有关杂环系统的有趣文章，而这些文章超出了经典有机化学的范畴。更积极的是，有许多研究领域都是杂原子化学的明显例子。其中包括以下结构和反应：（a）高度配位的主族元素化合物的异常化合价；（b）低配位的主族元素化合物的特征和异常性质；（c）高度应变的主族元素化合物的特征和异常性质；（d）主族化合物之间的相似性。NDS和过渡金属化合物；（e）导致高度反应性中间物种的杂原子参与的键的简单光化学或热裂解；（f）含有多重键合杂原子的化合物的异常反应；（g）高度链合杂原子的异常结构和反应；（h）特异和异常的杂原子对化合物物理和化学性质的ighboring基团效应；（i）对合成过程的有用影响；（j）对周期表中许多元素的广泛适用性，例如在超价物种中的配体耦合；对极其重要的wittig反应的变化；以及化合物碱的立体化学。d分子中存在的杂原子的影响。这些陈述并非旨在限制杂原子化学的范围，而是旨在说明杂原子在含有它们的化合物的化学中发挥重要作用的多种方式。
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Heteroatom Chemistry is designed to bring together a broad interdisciplinary group of chemists who work with compounds containing main-group elements of groups 13 through 17 of the Periodic Table and certain other related elements. The fundamental reactivity should in all cases be concentrated about the heteroatoms. It does not matter whether the compounds being studied are acyclic or cyclic; saturated or unsaturated; of a monomeric polymeric or solid state nature; inorganic organic or naturally occurring so long as the heteroatom is playing an essential role. Also both experimental articles and those based on computational chemistry are welcomed. In general Heteratom Chemistry will not accept manuscripts based on classical heterocyclic chemistry (for which several special journals are available). It welcomes however interesting articles on heterocyclic systems beyond the scope of classical organic chemistry. On a more positive note there are many areas of research that are unmistakable examples of heteroatom chemistry. These include structures and reactions that exhibit (a) unusual valency of highly coordinated main-group element compounds; (b) characteristics and unusual properties of low coordinate main-group element compounds; (c) characteristics and unusual properties of highly strained main-group element compounds; (d) similarities between main-group compounds and transition metal compounds; (e) facile photochemical or thermal cleavage of bonds involving heteroatoms that lead to highly reactive intermediate species; (f) the unusual reactivity of compounds that contain multiply bonded heteroatoms; (g) the unusual structures and reactivities of highly catenated heteroatoms; (h) specific and unusual neighboring group effects of heteroatoms on physical and chemical properties of compounds; (i) useful influences on synthetic processes; and (j) wide applicability over many elements of the Periodic Table e.g. ligand coupling within hypervalent species; variations on the immensely important Wittig reactions; and the stereochemistry of compounds based on the influence of heteroatoms present in the molecules. These statements are not designed to limit the scope of heteroatom chemistry; rather they are intended to illustrate the many ways in which heteroatoms play essential roles in the chemistry of compounds containing them.
